22 de ago. de 2009
18 de ago. de 2009
Angelina - Boa Vista
Enviado pelo meu aparelho BlackBerry®
16 de ago. de 2009
11 de ago. de 2009
Estilo de vida saudável previne doenças crônicas
The Los Angeles Times (8/11, Yurkiewicz) reports, "If people would just do four things -- engage in regular physical activity, eat a healthy diet, not smoke, and avoid becoming obese -- they could slash their risk of diabetes, heart attack, stroke or cancer by 80 percent," CDC researchers found. "But less than 10 percent of the 23,153 people in the multiyear study -- published in Monday's Archives of Internal Medicine -- actually lived their lives this way." The new study, however, may change some minds, because it has "such a simple straightforward focus on making the point that prevention works in preventing serious disease," noted Dr. J. Leonard Lichtenfeld, of the American Cancer Society.
Delving into the specifics of the study, HealthDay (8/10, Mozes) reported that CDC investigators, alongside scientists in Germany, "drew on data from a German study conducted between 1994 and 1998" in which participants between 35 and 65 years of age were asked about their "lifestyle characteristics," disease history, and dietary habits. "Adherence to four key lifestyle indicators were tracked: never having smoked; having a body-mass index below 30 (the threshold for obesity); exercising for a minimum of 3.5 hours per week; and eating healthfully, as evidenced by a diet high in fruit and vegetable intake, but low in meat." Although "most study participants engaged in some (one to three), but not all of the ideal behaviors," the team found that "less than four percent met none of the criteria for a healthy lifestyle, while nine percent followed all four."
As for disease incidence, "3.7 percent of participants developed diabetes, 0.9 percent developed myocardial infarction, 0.8 percent developed stroke, and 3.8 percent developed cancer," MedPage Today (8/10, Fiore) reported. Yet, participants "who followed all four lifestyle factors had a 78 percent lower risk of developing a chronic disease than those with no healthy factors." Specifically, they had a "93 percent lower risk of diabetes, an 81 percent lower risk of myocardial infarction, a 50 percent lower risk of stroke," and a "36 percent lower risk of cancer." And, "reductions in risk were similar for men and women."
WebMD (8/10, Stacy), the UK's Telegraph (8/11, Devlin) also covers the story, as did Time (8/10, Blue) in its Wellness blog.
7 de ago. de 2009
Antioxidant Supplements
Antioxidant Supplements Blunt Exercise-Induced Improvement of Insulin Sensitivity
Regardless of their previous exercise patterns, young men did not benefit from vitamin E or C supplementation.
Regular exercise increases insulin sensitivity and decreases risk for type 2 diabetes. One mechanism is known: Exercise stimulates glucose-transporter molecules to proliferate and move to the cell membrane, where they ferry glucose into the cell. Exercise also increases the formation of mitochondria, which give cells more energy but also create more harmful reactive oxygen species (ROS).
An international team randomized 39 young men (19 nonconditioned and 20 with prior physical conditioning) to exercise either with or without having ingested daily antioxidant supplements (1000-mg vitamin C and 400-IU vitamin E). In the groups that did not receive antioxidants, mean insulin sensitivity was higher after exercise among both nonconditioned and conditioned men; exercise raised production of ROS but also activated natural antioxidant systems. However, in both antioxidant groups, researchers noted no improvement in insulin sensitivity, and natural antioxidant systems were blunted.
Comment: Surprisingly, use of antioxidant supplements blunts the beneficial effects of regular exercise on insulin sensitivity, even though diets that are rich in fruits and vegetables (and, thus, contain high concentrations of antioxidants) lower risk for developing type 2 diabetes. Overall, little evidence of benefit from regular use of vitamin C or E supplements exists, and this study offers one reason to discourage their use and to encourage diets that are rich in fruits and vegetables.
Published in Journal Watch General Medicine June 4, 2009
Citation:
Ristow M et al. Antioxidants prevent health-promoting effects of physical exercise in humans. Proc Natl Acad Sci U S A 2009 May 26; 106:8665. [Free full-text online] [Medline® Abstract]
Copyright © 2009. Massachusetts Medical Society. All rights reserved.
6 de ago. de 2009
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